Disease information

Disease Name Huntington's Disease
Synonyms
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huntington's disease-like 1 | huntington's disease-like 2 | huntington's disease | huntington's chorea | huntington disease | huntington disease-like 1 | huntington disease-like 2 | huntington disease, late onset | akinetic-rigid variant of huntington disease | juvenile huntington disease | hd

Definition DO: A prion disease that is characterized by a phenocopy of Huntington disease (unwanted choreatic movements, behavioral and psychiatric disturbances and dementia) that has_material_basis_in autosomal dominant inheritance of 8 extra octapeptide repeats in the prion protein (PRNP) gene on chromosome 20p13.
Abbreviation HD
Organism Mus musculus
Tissue Type Liver
Pathogenic Factor genotype: Het (Q140) Knock-In;age: 2 month;Sex: Female
Control | Case GSM1605862;GSM1605863;GSM1605864;GSM1605865 GSM1605742;GSM1605743;GSM1605744;GSM1605745
Data Source GEO
Accession GSE65774
Data Type RNA-Seq
PubMed ID 26900923

Differential genes

Gene Name AveExpr Control AveExpr Case Log2FC P-value Adjusted P-value Regulation Boxplot

Volcano plot

Heatmap

Enriched regulations/functions/pathways


Not Available

ID Terms Size ES NES P-value Adjusted P-value Plot

Differential cell type markers

Cell Type Source Regulation Gene Ratio Bg Ratio Hypergeometric P-value Adjusted P-value Marker Gene Marker Gene

Diseases with correlated signatures

DSAID Disease Enrichment Score P-value Organism +/- Analysis