Disease information Differential genes Enriched regulations/functions/pathways Differential cell type markers Diseases with correlated signatures

Disease information

Disease Name Primary Progressive Multiple Sclerosis
Synonyms primary progressive multiple sclerosis|chronic progressive multiple sclerosis|multiple sclerosis, chronic progressive|multiple sclerosis, primary progressive|multiple sclerosis, secondary progressive
Definition DO: A multiple sclerosis that is characterized by steady worsening of neurologic functioning, without any distinct relapses or periods of remission. The rate of progression may vary over time, with occasional plateaus or temporary improvements, but the progression is continuous.
Abbreviation PPMS
Organism Homo sapiens
Tissue Type Peripheral blood
Cell Type B cells
Control | Case
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GSM5732852;GSM5732853;GSM5732854;GSM5732855;GSM5732856;GSM5732857;GSM5732858;GSM5732859;GSM5732860;GSM5732861;GSM5732862;GSM5732863;GSM5732864;GSM5732865;GSM5732866;GSM5732867;GSM5732868;GSM5732869;GSM5732870;GSM5732871;GSM5732872;GSM5732873;GSM5732874;GSM5732875;GSM5732876;GSM5732877;GSM5732878;GSM5732879
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GSM5732880;GSM5732881;GSM5732882;GSM5732883;GSM5732884;GSM5732885;GSM5732886;GSM5732887;GSM5732888;GSM5732889;GSM5732890;GSM5732891;GSM5732892
Data Source GEO
Accession GSE190847
Data Type Microarray
PubMed ID 36405756

Differential genes

Gene Name AveExpr Control AveExpr Case Log2FC P-value Adjusted P-value Regulation Boxplot

Volcano plot

Heatmap

Enriched regulations/functions/pathways


TF Regulation Gene Ratio Bg Ratio P-value Adjusted P-value Enriched Gene Enriched Gene Count

ID Terms Size ES NES P-value Adjusted P-value Plot

Differential cell type markers

Cell Type Source Regulation Gene Ratio Bg Ratio Hypergeometric P-value Adjusted P-value Marker Gene Marker Gene

Diseases with correlated signatures

DSAID Disease Enrichment Score P-value Organism +/- Analysis