Disease information Differential genes Enriched regulations/functions/pathways Differential cell type markers Diseases with correlated signatures

Disease information

Disease Name Acute Liver Failure
Synonyms fulminant hepatic failure|acute hepatic failure|acute liver failure|liver failure, acute
Definition HPO: Hepatic failure refers to the inability of the liver to perform its normal synthetic and metabolic functions, which can result in coagulopathy and alteration in the mental status of a previously healthy individual. Hepatic failure is defined as fulminant if there is onset of encephalopathy within 4 weeks of the onset of symptoms in a patient with a previously healthy liver.
Organism Homo sapiens
Tissue Type Liver
Pathogenic Factor origin: HBV-associated acute liver failure
Control | Case GSM366065;GSM366066;GSM366067;GSM366068;GSM366069;GSM366070;GSM366071;GSM366072 GSM366057;GSM366058;GSM366059;GSM366060;GSM366061;GSM366062;GSM366063;GSM366064
Data Source GEO
Accession GSE14668
Data Type Microarray
PubMed ID 20421498

Differential genes

Gene Name AveExpr Control AveExpr Case Log2FC P-value Adjusted P-value Regulation Boxplot

Volcano plot

Heatmap

Enriched regulations/functions/pathways


TF Regulation Gene Ratio Bg Ratio P-value Adjusted P-value Enriched Gene Enriched Gene Count

ID Terms Size ES NES P-value Adjusted P-value Plot

Differential cell type markers

Cell Type Source Regulation Gene Ratio Bg Ratio Hypergeometric P-value Adjusted P-value Marker Gene Marker Gene

Diseases with correlated signatures

DSAID Disease Enrichment Score P-value Organism +/- Analysis