Detail

Basic Information

GTO ID GTD0003
Accession GSE106695
Altered gene GRHL2
Gene xrefs Gene ID: 79977
Gene symbol: GRHL2
Ensembl ID: ENSG00000083307
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Treatment siGRHL2
RNA design information siRNA ID: 109594 (Ambion/ Thermo Fisher)
Control GSM2845505;GSM2845506;GSM2845507;GSM2845508
Case GSM2845511;GSM2845512;GSM2845513;GSM2845514;GSM2845515;GSM2845516
Disease Breast Cancer
Disease information Disease group: Cancer
Definition: A thoracic cancer that originates in the mammary gland.
Xref: DO:1612 | EFO:0000305 | EFO:0003869 | MONDO:0016419 | MSH:C562840 | NCI:C4503 | OMIM:114480 | ORDO:227535
Organism Homo sapiens
Characteristics siGRHL2 A, siRNA ID: 109594 (Ambion/ Thermo Fisher)
Strategy RNA-seq
Platform GPL16791

Differential genes

Volcano plot

−4−2024601020304050
Up(3727)Down(3799)Not Sig(19097)Log2FC-Log10(adjusted P-value)-0.0680.0681.3

Heatmap

GSM2845505GSM2845506GSM2845507GSM2845508GSM2845511GSM2845512GSM2845513GSM2845514GSM2845515GSM2845516
−2−1012Z-Score

Enriched regulations/functions/pathways




111213establishment of organelle localizationprotein localization to cell peripheryvesicle-mediated transport to the plasma membraneregulation of intracellular transportestablishment of vesicle localizationGolgi vesicle transportestablishment of protein localization to organellecytosolic transportmacroautophagyendosomal transport
-Log10(P-value)

Differential cell type markers