Detail

Basic Information

GTO ID GTD0002
Accession GSE106436
Altered gene Upf1
Gene xrefs Gene ID: 19704
Gene symbol: Upf1
Ensembl ID: ENSMUSG00000058301
Gene perturbation-related omics dataset PerturbAtlas
Treatment Upf1 ASO
Control GSM2837623;GSM2837624;GSM2837625;GSM2837626
Case GSM2837631;GSM2837632;GSM2837633
Disease Hemophilia
Disease information Disease group: Genetic Disease
Definition: A blood coagulation disease that has_material_basis_in Factor IX deficiency, which makes coagulation much more prolonged. The disease is inherited as an X-linked recessive trait.
Xref: DO:12259 | EFO:0009154 | ICD10:D67 | MONDO:0010604 | MSH:D002836 | NCI:C26721 | OMIM:306900 | ORDO:98879
Organism Mus musculus
Tissue/Cell type Liver
Characteristics Upf1 ASO
Strategy RNA-seq
Platform GPL17021

Differential genes

Gene Name AveExpr Control AveExpr Case Log2FC P-value Adjusted P-value Regulation Boxplot

Volcano plot

Heatmap

Enriched regulations/functions/pathways


TF Regulation Gene Ratio Bg Ratio P-value Adjusted P-value Enriched Gene Count

ID Terms Size ES NES P-value Adjusted P-value Plot


Differential cell type markers

Cell Type Source Regulation Gene Ratio Bg Ratio Hypergeometric P-value Adjusted P-value Marker Gene