Detail

Basic Information

GTO ID GTD0334
Accession E-MTAB-11315
Gene therapy-related clinical trial GTC2404
Altered gene S
Gene xrefs Gene ID: 1489668
Treatment ARCT-021(ARCT COVID-19 vaccine)
Control
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ARCT.101.1102.Day3_07;ARCT.101.1107.Day3_12;ARCT.101.2103.Day3_09;ARCT.101.2106.Day3_06;ARCT.101.2108.Day3_03;ARCT.101.2111.Day3_03;ARCT.101.3101.Day3_03;ARCT.101.3104.Day3_12;ARCT.101.4103.Day3_11;ARCT.101.4107.Day3_03;ARCT.101.4117.Day3_01;ARCT.101.4119.Day3_07;ARCT.101.5104.Day3_08;ARCT.101.5108.Day3_12;ARCT.101.5109.Day3_01;ARCT.101.5116.Day3_08;ARCT.101.6103.Day3_11;ARCT.101.6108.Day3_07;ARCT.101.6110.Day3_03;ARCT.101.6111.Day3_07;ARCT.101.7103.Day3_05;ARCT.101.7105.Day3_11;ARCT.101.7108.Day3_03;ARCT.101.7115.Day3_07;ARCT.101.8105.Day3_05;ARCT.101.8106.Day3_09;ARCT.101.8109.Day3_09;ARCT.101.8112.Day3_09
Case
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ARCT.101.3102.Day3_06;ARCT.101.3103.Day3_09;ARCT.101.3105.Day3_03;ARCT.101.3106.Day3_06;ARCT.101.3107.Day3_09
Disease COVID-19
Disease information Disease group: Infection
Definition: A Coronavirus infection that is characterized by fever, cough and shortness of breath and that has_material_basis_in SARS-CoV-2.
Xref: DO:0080600
Organism Homo sapiens
Tissue/Cell type blood
Characteristics Day3;10 microgram
Strategy Microarray
Platform A-MTAB-668

Differential genes

Volcano plot

−2−10123402468101214
Up(111)Down(19)Not Sig(435)Log2FC-Log10(adjusted P-value)-0.5170.5171.3

Heatmap

ARCT.101.1102.Day3_07ARCT.101.1107.Day3_12ARCT.101.2103.Day3_09ARCT.101.2106.Day3_06ARCT.101.2108.Day3_03ARCT.101.2111.Day3_03ARCT.101.3101.Day3_03ARCT.101.3104.Day3_12ARCT.101.4103.Day3_11ARCT.101.4107.Day3_03ARCT.101.4117.Day3_01ARCT.101.4119.Day3_07ARCT.101.5104.Day3_08ARCT.101.5108.Day3_12ARCT.101.5109.Day3_01ARCT.101.5116.Day3_08ARCT.101.6103.Day3_11ARCT.101.6108.Day3_07ARCT.101.6110.Day3_03ARCT.101.6111.Day3_07ARCT.101.7103.Day3_05ARCT.101.7105.Day3_11ARCT.101.7108.Day3_03ARCT.101.7115.Day3_07ARCT.101.8105.Day3_05ARCT.101.8106.Day3_09ARCT.101.8109.Day3_09ARCT.101.8112.Day3_09ARCT.101.3102.Day3_06ARCT.101.3103.Day3_09ARCT.101.3105.Day3_03ARCT.101.3106.Day3_06ARCT.101.3107.Day3_09
−202Z-Score

Enriched regulations/functions/pathways




303540regulation of T cell activationpositive regulation of cell activationmononuclear cell proliferationlymphocyte proliferationleukocyte mediated immunityregulation of leukocyte proliferationadaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsleukocyte proliferationpositive regulation of cytokine productioncytokine-mediated signaling pathway
-Log10(P-value)

Differential cell type markers