Detail

Basic Information

GTO ID GTD0333
Accession E-MTAB-11315
Gene therapy-related clinical trial GTC2404
Altered gene S
Gene xrefs Gene ID: 1489668
Treatment ARCT-021(ARCT COVID-19 vaccine)
Control
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ARCT.101.1102.Day3_07;ARCT.101.1107.Day3_12;ARCT.101.2103.Day3_09;ARCT.101.2106.Day3_06;ARCT.101.2108.Day3_03;ARCT.101.2111.Day3_03;ARCT.101.3101.Day3_03;ARCT.101.3104.Day3_12;ARCT.101.4103.Day3_11;ARCT.101.4107.Day3_03;ARCT.101.4117.Day3_01;ARCT.101.4119.Day3_07;ARCT.101.5104.Day3_08;ARCT.101.5108.Day3_12;ARCT.101.5109.Day3_01;ARCT.101.5116.Day3_08;ARCT.101.6103.Day3_11;ARCT.101.6108.Day3_07;ARCT.101.6110.Day3_03;ARCT.101.6111.Day3_07;ARCT.101.7103.Day3_05;ARCT.101.7105.Day3_11;ARCT.101.7108.Day3_03;ARCT.101.7115.Day3_07;ARCT.101.8105.Day3_05;ARCT.101.8106.Day3_09;ARCT.101.8109.Day3_09;ARCT.101.8112.Day3_09
Case
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ARCT.101.4101.Day3_03;ARCT.101.4102.Day3_07;ARCT.101.4104.Day3_03;ARCT.101.4105.Day3_07;ARCT.101.4106.Day3_11;ARCT.101.4115.Day3_07;ARCT.101.4116.Day3_10;ARCT.101.4118.Day3_04;ARCT.101.4120.Day3_02;ARCT.101.4121.Day3_05
Disease COVID-19
Disease information Disease group: Infection
Definition: A Coronavirus infection that is characterized by fever, cough and shortness of breath and that has_material_basis_in SARS-CoV-2.
Xref: DO:0080600
Organism Homo sapiens
Tissue/Cell type blood
Characteristics Day3;7.5 microgram
Strategy Microarray
Platform A-MTAB-668

Differential genes

Volcano plot

−2−10123051015
Up(107)Down(37)Not Sig(421)Log2FC-Log10(adjusted P-value)-0.3430.3431.3

Heatmap

ARCT.101.1102.Day3_07ARCT.101.1107.Day3_12ARCT.101.2103.Day3_09ARCT.101.2106.Day3_06ARCT.101.2108.Day3_03ARCT.101.2111.Day3_03ARCT.101.3101.Day3_03ARCT.101.3104.Day3_12ARCT.101.4103.Day3_11ARCT.101.4107.Day3_03ARCT.101.4117.Day3_01ARCT.101.4119.Day3_07ARCT.101.5104.Day3_08ARCT.101.5108.Day3_12ARCT.101.5109.Day3_01ARCT.101.5116.Day3_08ARCT.101.6103.Day3_11ARCT.101.6108.Day3_07ARCT.101.6110.Day3_03ARCT.101.6111.Day3_07ARCT.101.7103.Day3_05ARCT.101.7105.Day3_11ARCT.101.7108.Day3_03ARCT.101.7115.Day3_07ARCT.101.8105.Day3_05ARCT.101.8106.Day3_09ARCT.101.8109.Day3_09ARCT.101.8112.Day3_09ARCT.101.4101.Day3_03ARCT.101.4102.Day3_07ARCT.101.4104.Day3_03ARCT.101.4105.Day3_07ARCT.101.4106.Day3_11ARCT.101.4115.Day3_07ARCT.101.4116.Day3_10ARCT.101.4118.Day3_04ARCT.101.4120.Day3_02ARCT.101.4121.Day3_05
−202Z-Score

Enriched regulations/functions/pathways




354045leukocyte mediated immunityregulation of leukocyte proliferationregulation of T cell activationregulation of cell-cell adhesionregulation of leukocyte cell-cell adhesionleukocyte proliferationadaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsleukocyte cell-cell adhesionpositive regulation of cytokine productioncytokine-mediated signaling pathway
-Log10(P-value)

Differential cell type markers