Single-cell overall analysis Basic information Differential genes Enriched regulations/functions/pathways Differential cell type markers
Single-cell cluster analysis Cell clustering Marker genes Differential genes in clusters

Single-cell overall analysis

Detail

Basic Information

GTO ID GTD0075
Accession GSE164551
Gene therapy-related clinical trial GTC1583
Altered gene BCMA
Gene xrefs Gene ID: 608
Gene symbol: TNFRSF17
Ensembl ID: ENSG00000048462
Treatment BCMA CAR-T cell
Control GSM5013821
Case GSM5013825
Disease Multiple Myeloma
Disease information Disease group: Cancer
Definition: A myeloid neoplasm that is located_in the plasma cells in bone marrow.
Xref: DO:9538 | EFO:0001378 | HPO:HP:0006775 | ICD10:C90.0 | MONDO:0009693 | MSH:D009101 | NCI:C3242 | OMIM:254500 | ORDO:29073
Organism Homo sapiens
Tissue/Cell type Bone Marrow
Characteristics 8 months after first infusion
Strategy scRNA-seq
Platform GPL20795

Differential genes

Gene Name Log2FC Pct_Control Pct_Case P-value Adjusted P-value Regulation Boxplot

Volcano plot

Enriched regulations/functions/pathways


TF Regulation Gene Ratio Bg Ratio P-value Adjusted P-value Enriched Gene Count

ID Terms Size ES NES P-value Adjusted P-value Plot


Differential cell type markers

Cell Type Source Regulation Gene Ratio Bg Ratio Hypergeometric P-value Adjusted P-value Marker Gene

Single-cell cluster analysis

Cell clustering

Cell ratio

Marker genes

Gene Name Log2FC Pct_Control Pct_Case P-value Adjusted P-value Cluster Violin plot

Differential genes in clusters

Gene Name Log2FC Pct_Control Pct_Case P-value Adjusted P-value Cluster Boxplot