Gene symbol | IL2 | Synonyms | IL-2, TCGF, lymphokine | Type of gene | protein-coding |
Chromosome | 4 | Map location | 4q27 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | interleukin 2 |
Gene symbol | TNF | Synonyms | DIF, TNF-alpha, TNFA, TNFSF2, TNLG1F | Type of gene | protein-coding |
Chromosome | 6 | Map location | 6p21.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | tumor necrosis factor |
GTO ID | GTC4006 |
Trial ID | NCT04695327 |
Disease | Solid Tumor |
Altered gene | E1A|TNFa|IL-2 |
Therapeutic/Target gene | Therapeutic gene |
Therapy | DNA oncolytic virus |
Treatment | TILT-123|igrelimogene litadenorepvec |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | A Phase 1, Open-Label, Dose-escalation Clinical Trial of Tumor Necrosis Factor Alpha and Interleukin-2 Coding Oncolytic Adenovirus (TILT-123) in Patients With Injectable Solid Tumors |
Year | 2021 |
Country | Finland |
Company sponsor | TILT Biotherapeutics Ltd. |
Other ID(s) | TILT-T115|2020-001778-31 |
Vector information | |||||||||||||||
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