| Vector | adenovirus |
| Construct | Ad5-AFP-delta24-RGD |
| Vector type | recombinant replication-competent serotype 5-based adenovirus |
| Regulatory element | AFP promoter |
| Viral genome modification | E1B and partial E3 genes was deleted |
| Vector production method | For the construction of the corresponding lentiviral vectors, the OVA, fluorescence protein coding sequence, or the annealed shRNA oligonucleotides and miRNA199a were inserted between the restriction sites in the lentiviral transfer plasmids. The lentiviral particles were produced by transient 4-plasmid co-transfection in the HEK293T cell line, concentrated by ultracentrifugation, and then tittered. |
| Additional feature | GM-CSF |
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