Gene symbol | TERT | Synonyms | CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT | Type of gene | protein-coding |
Chromosome | 5 | Map location | 5p15.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | telomerase reverse transcriptase |
GTO ID | GTC3975 |
Trial ID | NCT04391049 |
Disease | Squamous Cell Carcinoma |
Altered gene | E1A|E1B|TERT |
Therapeutic/Target gene | Therapeutic gene |
Therapy | DNA oncolytic virus |
Treatment | Telomelysin|OBP-301 |
Co-treatment | carboplatin|paclitaxel|radiation |
Phase | Phase1 |
Recruitment status | Active, Not Recruiting |
Title | Phase I Trial With Expansion Cohort of OBP-301 (Telomelysin™) and Definitive Chemoradiation for Patients With Locally Advanced Esophageal and Gastroesophageal Cancer Who Are Not Candidates for Surgery |
Year | 2021 |
Country | United States |
Company sponsor | NRG Oncology |
Other ID(s) | NRG-GI007|NCI-2020-02320|NRG-GI007|NRG-GI007|U10CA180868 |
Vector information | |||||||||||
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Cohort 1 | |||||||||
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