Gene symbol | TERT | Synonyms | CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT | Type of gene | protein-coding |
Chromosome | 5 | Map location | 5p15.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | telomerase reverse transcriptase |
GTO ID | GTC3971 |
Trial ID | NCT03172819 |
Disease | Advanced Solid Tumor |
Altered gene | E1A|E1B|TERT |
Therapeutic/Target gene | Therapeutic gene |
Therapy | DNA oncolytic virus |
Treatment | Telomelysin|OBP-301 |
Co-treatment | Pembrolizumab |
Phase | Phase1 |
Recruitment status | Completed |
Title | An Open Label Phase I Study to Evaluate the Safety and Efficacy of OBP-301 With Pembrolizumab in Patients With Advanced Solid Tumors |
Year | 2017 |
Country | Japan |
Company sponsor | Toshihiko Doi |
Other ID(s) | EPOC1505 |
Vector information | |||||||||||
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Cohort 1 | |||||||||
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