Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3940
Trial ID NCT06497361
Disease Lupus Nephritis
Altered gene BCMA|CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment PRG-2311
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleSafety and Efficacy of PRG-2311 (CD19/BCMA-targeting CAR-T Cells) for Refractory Lupus Nephritis and IgG4-Related Disease
Year2024
CountryChina
Company sponsorTongji Hospital
Other ID(s)S114

Clinical Result

Cohort 1
Administration route infusion
Dosage 3.5E7 cells, 1.0E8 cells, 3.0E8 cells
Pts 30
Age Adult, Older_Adult
Lymph depletion Yes

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