Basic Information

Gene symbol VEGFA Synonyms L-VEGF, MVCD1, VEGF, VPF Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description vascular endothelial growth factor A

GTO ID GTC3938
Trial ID NCT06492876
Disease Diabetic Macular Edema
Altered gene VEGFA
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment FT-003
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleA Dose-escalation and Dose-expanded Phase I/II Clinical Study to Evaluate the Safety, and Efficacy of FT-003 in Subjects With DME
Year2024
CountryChina
Company sponsorFrontera Therapeutics
Other ID(s)FT003-CD101
Vector information
Vectoradeno-associated virus
ConstructAAV-VEGFA
Vector typeadeno-associated virus (AAV) vector
Transgene/Inserted genehuman VEGFA gene

Clinical Result

Cohort 1
Administration route intravitreal injection
Pts 78
Age Adult, Older_Adult

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