Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3932
Trial ID NCT06486051
Disease Large B-Cell Lymphoma | Diffuse Large B-Cell Lymphoma | Primary Mediastinal Large B-Cell Lymphoma | Non-Hodgkin's Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment WZTL-002 CAR T-cells
PhasePhase2
Recruitment statusNot Recruiting
TitleA Phase 2 Trial to Evaluate the Efficacy and Safety of WZTL-002 in Patients With Relapsed or Refractory Large B-cell Lymphoma (ENABLE-2)
Year2024
CountryNew Zealand
Company sponsorMalaghan Institute of Medical Research
Other ID(s)WZTL002-2|U1111-1305-7917

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 0.85E6 cells/kg of body weight
Donor type autologous
Pts 60
Age Adult, Older_Adult
Lymph depletion Yes

Relationship Graph

Overview of Knowledge Graph