Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3931
Trial ID NCT06485232
Disease Neuromyelitis Optica Spectrum Disorder | Generalized Myasthenia Gravis | Multiple Sclerosis | Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Altered gene BCMA|CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment BCMA/CD19 CAR-T cells
PhaseEarly_Phase1
Recruitment statusNot Recruiting
TitleAn Exploratory Study on the Safety and Efficacy of Universal CAR-T Cells Targeting BCMA and CD19 in the Treatment of Refractory Autoimmune Diseases of the Nervous System
Year2024
CountryChina
Company sponsorXuanwu Hospital, Beijing
Other ID(s)2024-BRL-302-02

Clinical Result

Cohort 1
Administration route infusion
Pts 25
Age Adult, Older_Adult

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