Gene symbol | TNFRSF17 | Synonyms | BCM, BCMA, CD269, TNFRSF13A | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p13.13 | dbXrefs | |
Description | TNF receptor superfamily member 17 |
Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
GTO ID | GTC3931 |
Trial ID | NCT06485232 |
Disease | Neuromyelitis Optica Spectrum Disorder | Generalized Myasthenia Gravis | Multiple Sclerosis | Chronic Inflammatory Demyelinating Polyradiculoneuropathy |
Altered gene | BCMA|CD19 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | BCMA/CD19 CAR-T cells |
Phase | Early_Phase1 |
Recruitment status | Not Recruiting |
Title | An Exploratory Study on the Safety and Efficacy of Universal CAR-T Cells Targeting BCMA and CD19 in the Treatment of Refractory Autoimmune Diseases of the Nervous System |
Year | 2024 |
Country | China |
Company sponsor | Xuanwu Hospital, Beijing |
Other ID(s) | 2024-BRL-302-02 |
Cohort 1 | |||||||
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