Basic Information

Gene symbol CD276 Synonyms 4Ig-B7-H3, B7-H3, B7H3, B7RP-2 Type of gene protein-coding
Description CD276 molecule

GTO ID GTC3928
Trial ID NCT06482905
Disease High Grade Glioma
Altered gene CD276
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment TX103
PhasePhase1
Recruitment statusNot Recruiting
TitleA Phase I, Open-Label, Single/Multiple Dose, Dose-escalation Study to Evaluate the Safety, Tolerability and Antitumor Activity of TX103 CAR-T Cell Injection (TX103) in Subjects With Recurrent or Progressive Grade 4 Glioma.
Year2024
CountryChina
Company sponsorTcelltech Inc.
Other ID(s)TX103T-RG008

Clinical Result

Cohort 1
Administration route intracavitary injection
Dosage 6E7 cells, 1.5E8 cells, 2.5E8 cells
Pts 52
Age Adult, Older_Adult

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