Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3927
Trial ID NCT06482684
Disease Mantle Cell Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment KTE-X19|Tecartus|Brexucabtagene autoleucel
Co-treatment Ibrutinib|Rituximab
Location approved US, EU, UK, Australia, Canada
PhasePhase2
Recruitment statusRecruiting
TitleEarly Treatment Intensification in Patients With High Risk Mantle Cell Lymphoma Using CAR-T-cell Treatment After an Abbreviated Induction Therapy With Rituximab and Ibrutinib and 6 Months Ibrutinib Maintenance (Arm A) as Compared to Standard of Care Induction and Maintenance (Arm B)
Year2024
CountryGermany
Company sponsorChristian Schmidt, MD
Other ID(s)CARMAN|2022-502405-15-01

Clinical Result

Cohort 1
Administration route None
Pts 150
Age Adult, Older_Adult
Lymph depletion Yes

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