Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
GTO ID | GTC3927 |
Trial ID | NCT06482684 |
Disease | Mantle Cell Lymphoma |
Altered gene | CD19 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | KTE-X19|Tecartus|Brexucabtagene autoleucel |
Co-treatment | Ibrutinib|Rituximab |
Location approved | US, EU, UK, Australia, Canada |
Phase | Phase2 |
Recruitment status | Recruiting |
Title | Early Treatment Intensification in Patients With High Risk Mantle Cell Lymphoma Using CAR-T-cell Treatment After an Abbreviated Induction Therapy With Rituximab and Ibrutinib and 6 Months Ibrutinib Maintenance (Arm A) as Compared to Standard of Care Induction and Maintenance (Arm B) |
Year | 2024 |
Country | Germany |
Company sponsor | Christian Schmidt, MD |
Other ID(s) | CARMAN|2022-502405-15-01 |
Cohort 1 | |||||||||
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