Basic Information

Gene symbol CD70 Synonyms CD27-L, CD27L, CD27LG, LPFS3, TNFSF7, TNLG8A Type of gene protein-coding
Description CD70 molecule

GTO ID GTC3923
Trial ID NCT06480565
Disease Clear Cell Renal Cell Carcinoma
Altered gene CD70
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment ADI-270
PhasePhase1|Phase2
Recruitment statusNot Recruiting
TitleA Phase 1/2 Trial of ADI-270 (Engineered γδ Chimeric Receptor [CAR] Vδ1 T Cells Targeting CD70) in Adults With Relapsed or Refractory (R/R) Clear Cell Renal Cell Carcinoma (ccRCC)
Year2024
CountryUnited States
Company sponsorAdicet Therapeutics
Other ID(s)ADI-202427001

Clinical Result

Cohort 1
Administration route None
Pts 60
Age Adult, Older_Adult
Lymph depletion Yes

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