Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding | |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | Entrez:930 MIM:107265 HGNC:HGNC:1633 Ensembl:ENSG00000177455 AllianceGenome:HGNC:1633 | |
Description | CD19 molecule |
GTO ID | GTC3920 |
Trial ID | NCT06475495 |
Disease | Rheumatoid Arthritis |
Altered gene | CD19 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | KYV-101 |
Phase | Phase1|Phase2 |
Recruitment status | Not Recruiting |
Title | Comparison of B-cell Depletion by Rituximab and Anti-CD 19 CAR-T Therapy in Patients With Rheumatoid Arthritis. Two-stage Interventional, Prospective, Randomized, Controlled, Open Label, Parallel-group Phase I/II Trial in Patients With Active, ACPA-positive and Treatment Refractory Rheumatoid Arthritis |
Year | 2024 |
Country | Germany |
Company sponsor | Charite University, Berlin, Germany |
Other ID(s) | CCM-RNT-202401|2024-514955-13-00 |
Cohort 1 | |||||||||
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