Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3920
Trial ID NCT06475495
Disease Rheumatoid Arthritis
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment KYV-101
PhasePhase1|Phase2
Recruitment statusNot Recruiting
TitleComparison of B-cell Depletion by Rituximab and Anti-CD 19 CAR-T Therapy in Patients With Rheumatoid Arthritis. Two-stage Interventional, Prospective, Randomized, Controlled, Open Label, Parallel-group Phase I/II Trial in Patients With Active, ACPA-positive and Treatment Refractory Rheumatoid Arthritis
Year2024
CountryGermany
Company sponsorCharite University, Berlin, Germany
Other ID(s)CCM-RNT-202401|2024-514955-13-00

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Pts 13
Age Adult, Older_Adult

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