Gene symbol | MUC16 | Synonyms | CA125 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19p13.2 | dbXrefs | |
Description | mucin 16, cell surface associated |
GTO ID | GTC3916 |
Trial ID | NCT06469281 |
Disease | Epithelial Ovarian Cancer | Primary Peritoneal Carcinoma | Fallopian Tube Cancer |
Altered gene | MUC16 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | 27T51 |
Phase | Phase1 |
Recruitment status | Not Recruiting |
Title | A Phase 1a/1b Study of 27T51, an Anti-MUC16 CAR T Cell Drug Product Administered Alone or in Combination for Participants With Recurrent or Refractory Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer |
Year | 2024 |
Country | United States |
Company sponsor | Regeneron Pharmaceuticals |
Other ID(s) | 27T51-01 |
Cohort1: CAR-T | |||||
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Cohort2: CAR-T_Cemiplimab | |||||
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Cohort3: CAR-T_Cemiplimab_Bevacizumab | |||||
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