Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3909
Trial ID NCT06464861
Disease Primary Mediastinal B-Cell Lymphoma | Mantle Cell Lymphoma | Diffuse Large B Cell Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell|CAR-NK cell
Treatment CD19 CAR-NK/T cells
PhasePhase1
Recruitment statusNot Recruiting
TitleSequential Treatment With 7x19 CAR-T After Umbilical Cord Blood Derived CD19 CARNK in Relapsed/Refractory B Cell Lymphoma
Year2024
CountryChina
Company sponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University
Other ID(s)2024 (0673)

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage CAR-NK019: 2E6 cells/kg at day 0; CAR-T: 2E6 cells/kg after 1 week
Pts 52
Age Adult, Older_Adult

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