Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1


GTO ID GTC3907
Trial ID NCT06464185
Disease B-Cell Non-Hodgkin's Lymphoma
Altered gene CD3|CD19|CD20
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CAR-T cells
Co-treatment Obinutuzumab|Glofitamab
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleA Prospective Clinical Study of CD3-CD20 Bisspecific Antibody Based Therapy Combined With CD19-CAR T Cells in the Treatment of Relapsed Refractory B-cell Non-Hodgkin Lymphoma
Year2024
CountryChina
Company sponsorInstitute of Hematology & Blood Diseases Hospital, China
Other ID(s)IIT2024021

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Pts 27
Age Adult, Older_Adult
Lymph depletion Yes

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