Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding | |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | Entrez:930 MIM:107265 HGNC:HGNC:1633 Ensembl:ENSG00000177455 AllianceGenome:HGNC:1633 | |
Description | CD19 molecule |
Gene symbol | MS4A1 | Synonyms | B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 | Type of gene | protein-coding | |
Chromosome | 11 | Map location | 11q12.2 | dbXrefs | Entrez:931 MIM:112210 HGNC:HGNC:7315 Ensembl:ENSG00000156738 AllianceGenome:HGNC:7315 | |
Description | membrane spanning 4-domains A1 |
GTO ID | GTC3907 |
Trial ID | NCT06464185 |
Disease | B-Cell Non-Hodgkin's Lymphoma |
Altered gene | CD3|CD19|CD20 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CAR-T cells |
Co-treatment | Obinutuzumab|Glofitamab |
Phase | Phase1|Phase2 |
Recruitment status | Recruiting |
Title | A Prospective Clinical Study of CD3-CD20 Bisspecific Antibody Based Therapy Combined With CD19-CAR T Cells in the Treatment of Relapsed Refractory B-cell Non-Hodgkin Lymphoma |
Year | 2024 |
Country | China |
Company sponsor | Institute of Hematology & Blood Diseases Hospital, China |
Other ID(s) | IIT2024021 |
Cohort 1 | |||||||||||
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