Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | MS4A1 | Synonyms | B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11q12.2 | dbXrefs | |
Description | membrane spanning 4-domains A1 |
GTO ID | GTC3905 |
Trial ID | NCT06462144 |
Disease | Systemic Lupus Erythematosus | Vasculitis | Idiopathic Inflammatory Myopathy |
Altered gene | CD19|CD20 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | IMPT-514 |
Phase | Early_Phase1 |
Recruitment status | Not Recruiting |
Title | An Exploartory Trial of IMPT-514, An Autologous Anti-CD19/20 CAR T Therapy in Participants With Active, Refractory Systemic Lupus Erythematosus, Anca-associated Vasculitis, and Idiopathic Inflammatory Myopathy |
Year | 2024 |
Country | China |
Company sponsor | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School |
Other ID(s) | RD17-01 |
Cohort 1 | |||||||||||
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