Basic Information

Gene symbol ANGPTL3 Synonyms ANG-5, ANGPT5, ANL3, FHBL2 Type of gene protein-coding
Description angiopoietin like 3

GTO ID GTC3899
Trial ID NCT06451770
Disease Hypercholesterolemia
Altered gene ANGPTL3
Therapeutic/Target gene Target gene
TherapyGene editing
Treatment VERVE-201
PhasePhase1
Recruitment statusNot Recruiting
TitleA Phase 1b Single Ascending Dose Study to Evaluate the Safety of VERVE-201 in Patients With Refractory Hyperlipidemia
Year2024
CountryUnited States
Company sponsorVerve Therapeutics, Inc.
Other ID(s)VT-20101
Vector information
Vectorlipid nanoparticle

Clinical Result

Cohort 1
Administration route intravenous infusion
Pts 36
Age Adult, Older_Adult

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