Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3898
Trial ID NCT06451159
Disease Multiple Sclerosis
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment KYV-101
PhasePhase1
Recruitment statusRecruiting
TitlePhase 1, Open-Label, Single Center Study of KYV-101, an Autologous Fully-Human Anti-CD19 Chimeric Antigen Receptor T Cell (CD19 CAR T) Therapy, in Participants With Treatment Refractory Progressive Multiple Sclerosis
Year2024
CountryUnited States
Company sponsorBruce Cree
Other ID(s)23-40657

Clinical Result

Cohort 1
Administration route infusion
Dosage 0.33E8 cells, 1E8 cells
Donor type autologous
Pts 10
Age Adult, Older_Adult
Lymph depletion Yes

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