Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC3895
Trial ID NCT06445803
Disease Acute Lymphoblastic Leukemia | B-Cell Lymphoma
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment KQ-2002 CAR-T cells|CD19/CD22 CAR T-cells
PhasePhase1
Recruitment statusRecruiting
TitleA Preliminary Study to Evaluate the Safety, Tolerability, Preliminary Efficacy and Pharmacokinetic Profile of KQ-2002 (CD19/CD22 CAR-T) in Adults With Recurrent or Refractory Acute Lymphoblastic Leukemia or Non-Hodgkin's Lymphoma
Year2024
CountryChina
Company sponsorRong Tao
Other ID(s)KQ-2002-XC001

Clinical Result

Cohort 1
Administration route infusion
Dosage 0.5~5.0E6 cells/kg
Pts 48
Age Adult, Older_Adult
Lymph depletion Yes

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