Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3885
Trial ID NCT06420154
Disease Systemic Lupus Erythematosus | Sjogren's Syndrome | Systemic Sclerosis | Inflammatory Myopathy | Vasculitis | Antiphospholipid Syndrome
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
PhaseEarly_Phase1
Recruitment statusNot Recruiting
TitleAn Exploratory Clinical Study to Evaluating the Safety and Efficacy of Infusiing Anti-CD19-CAR-T Cells Injection (Anti-CD19-CAR-T Cells) in Patients With Relapsed/Refractory Autoimmune Diseases
Year2024
CountryChina
Company sponsorFirst Affiliated Hospital of Wenzhou Medical University
Other ID(s)CD19-CN-A4

Clinical Result

Cohort 1
Administration route infusion
Dosage 1E5 cells/kg, 3E5 cells/kg, 1E6 cells/kg
Donor type autologous
Pts 9
Age Adult, Older_Adult
Lymph depletion Yes

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