Basic Information

Gene symbol CD5 Synonyms LEU1, T1 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD5 molecule

GTO ID GTC3884
Trial ID NCT06420089
Disease T Cell Non-Hodgkin's Lymphoma
Altered gene CD5
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment Senza5 CART5
PhasePhase1
Recruitment statusNot Recruiting
TitleCD5-deleted Chimeric Antigen Receptor Cells (Senza5 CART5) to Enhance Immunotherapy Against T Cell Non-Hodgkin Lymphoma (NHL): a First-in-human Phase I Clinical Trial
Year2024
CountryUnited States
Company sponsorVittoria Biotherapeutics
Other ID(s)VIPER 101

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type autologous
Pts 30
Age Adult, Older_Adult
Lymph depletion Yes

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