Basic Information

Gene symbol CD5 Synonyms LEU1, T1 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD5 molecule

Gene symbol CD7 Synonyms GP40, LEU-9, TP41, Tp40 Type of gene protein-coding
Description CD7 molecule

GTO ID GTC3883
Trial ID NCT06420076
Disease T Cell Lymphoma | T-Cell Acute Lymphoblastic Leukemia
Altered gene CD5|CD7
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD5/CD7 CAR-T
Co-treatment chemotherapy
PhasePhase1|Phase2
Recruitment statusNot Recruiting
TitleThis is an Open, Single-arm, Clinical Study to Evaluate the Efficacy and Safety of Anti-CD7/CD5 CAR-T Cells in the Treatment of Relapsed or Refractory T-cell Acute Lymphoblastic Leukemia (T-ALL), ETP-ALL, and Lymphoblastic Lymphoma (TLBL).
Year2024
CountryChina
Company sponsorEssen Biotech
Other ID(s)ESBI202496

Clinical Result

Cohort 1
Administration route intravenous infusion
Pts 60
Age Child, Adult, Older_Adult
Lymph depletion Yes

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