Gene symbol | CD5 | Synonyms | LEU1, T1 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11q12.2 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | CD5 molecule |
Gene symbol | CD7 | Synonyms | GP40, LEU-9, TP41, Tp40 | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17q25.3 | dbXrefs | |
Description | CD7 molecule |
GTO ID | GTC3883 |
Trial ID | NCT06420076 |
Disease | T Cell Lymphoma | T-Cell Acute Lymphoblastic Leukemia |
Altered gene | CD5|CD7 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD5/CD7 CAR-T |
Co-treatment | chemotherapy |
Phase | Phase1|Phase2 |
Recruitment status | Not Recruiting |
Title | This is an Open, Single-arm, Clinical Study to Evaluate the Efficacy and Safety of Anti-CD7/CD5 CAR-T Cells in the Treatment of Relapsed or Refractory T-cell Acute Lymphoblastic Leukemia (T-ALL), ETP-ALL, and Lymphoblastic Lymphoma (TLBL). |
Year | 2024 |
Country | China |
Company sponsor | Essen Biotech |
Other ID(s) | ESBI202496 |
Cohort 1 | |||||||||
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