Basic Information

Gene symbol IL3RA Synonyms CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra Type of gene protein-coding
Description interleukin 3 receptor subunit alpha

Gene symbol CD33 Synonyms CD33rSiglec, SIGLEC-3, SIGLEC3, p67 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD33 molecule

GTO ID GTC3882
Trial ID NCT06420063
Disease Acute Myeloid Leukemia
Altered gene CD123|CD33
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD123/CD33 CAR-T cells
PhasePhase1|Phase2
Recruitment statusNot Recruiting
TitleSequential CAR-T Cell Infusion Targeting CD33 and CD123 for Refractory/Relapsed Acute Myeloid Leukaemia
Year2024
CountryChina
Company sponsorEssen Biotech
Other ID(s)ESBI202495

Clinical Result

Cohort 1
Administration route intravenous infusion
Pts 85
Age Child, Adult, Older_Adult
Lymph depletion Yes

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