Gene symbol | IL3RA | Synonyms | CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra | Type of gene | protein-coding |
Chromosome | X|Y | Map location | X;Y | dbXrefs | |
Description | interleukin 3 receptor subunit alpha |
Gene symbol | CD33 | Synonyms | CD33rSiglec, SIGLEC-3, SIGLEC3, p67 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.41 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | CD33 molecule |
GTO ID | GTC3882 |
Trial ID | NCT06420063 |
Disease | Acute Myeloid Leukemia |
Altered gene | CD123|CD33 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD123/CD33 CAR-T cells |
Phase | Phase1|Phase2 |
Recruitment status | Not Recruiting |
Title | Sequential CAR-T Cell Infusion Targeting CD33 and CD123 for Refractory/Relapsed Acute Myeloid Leukaemia |
Year | 2024 |
Country | China |
Company sponsor | Essen Biotech |
Other ID(s) | ESBI202495 |
Cohort 1 | |||||||||
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