Basic Information

Gene symbol GPC3 Synonyms DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1 Type of gene protein-coding
Description glypican 3

GTO ID GTC3877
Trial ID NCT06412458
Disease Osteosarcoma
Altered gene GPC3
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment IM83 CAR-T cells
PhasePhase1
Recruitment statusNot Recruiting
TitlePhase I Clinical Study to Evaluate the Safety and Efficacy of IM83 CAR-T Cells for the Treatment of Relapsed or Refractory Osteosarcoma
Year2024
CountryChina
Company sponsorBeijing Immunochina Medical Science & Technology Co., Ltd.
Other ID(s)IM83-002

Clinical Result

Cohort 1
Administration route infusion
Dosage 5E8 cells, 1E9 cells, 2E9 cells
Pts 9
Age Child, Adult, Older_Adult
Lymph depletion Yes

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