Gene symbol | CD22 | Synonyms | SIGLEC-2, SIGLEC2 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | CD22 molecule |
GTO ID | GTC3875 |
Trial ID | NCT06408194 |
Disease | Leukemia | Acute Lymphoblastic Leukemia |
Altered gene | CD22 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD22 CAR-T cells |
Co-treatment | Tisagenlecleucel |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | Phase I/Ib Clinical Trial of Autologous CD22 Chimeric Antigen Receptor (CAR) T Cells Following Commercial CD19 CAR T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies |
Year | 2024 |
Country | United States |
Company sponsor | Stanford University |
Other ID(s) | IRB-74214|NCI-2024-04331 |
Cohort 1 | |||||||||||
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