Basic Information

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC3875
Trial ID NCT06408194
Disease Leukemia | Acute Lymphoblastic Leukemia
Altered gene CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD22 CAR-T cells
Co-treatment Tisagenlecleucel
PhasePhase1
Recruitment statusRecruiting
TitlePhase I/Ib Clinical Trial of Autologous CD22 Chimeric Antigen Receptor (CAR) T Cells Following Commercial CD19 CAR T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies
Year2024
CountryUnited States
Company sponsorStanford University
Other ID(s)IRB-74214|NCI-2024-04331

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Pts 20
Age Child, Adult
Lymph depletion Yes

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