Gene symbol | NR2E3 | Synonyms | ESCS, PNR, RNR, RP37, rd7 | Type of gene | protein-coding |
Chromosome | 15 | Map location | 15q23 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | nuclear receptor subfamily 2 group E member 3 |
GTO ID | GTC3867 |
Trial ID | NCT06388200 |
Disease | Retinitis Pigmentosa |
Altered gene | NR2E3 |
Therapeutic/Target gene | Therapeutic gene |
Therapy | Gene transfer |
Treatment | OCU400-301 |
Phase | Phase3 |
Recruitment status | Recruiting |
Title | A Phase 3, Multi-Center, Randomized Study to Assess The Efficacy, Safety and Tolerability of Subretinal OCU400 Gene Therapy for the Treatment of Retinitis Pigmentosa |
Year | 2024 |
Country | United States |
Company sponsor | Ocugen |
Other ID(s) | OCU400-301 |
Vector information | |||||||||
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Cohort1: RHO mutations arm | |||||||||
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Cohort2: Gene agnostic arm | |||||||||
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