Basic Information

Gene symbol DLL3 Synonyms SCDO1 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description delta like canonical Notch ligand 3

GTO ID GTC3865
Trial ID NCT06384482
Disease Small Cell Lung Cancer | Lung Large Cell Neuroendocrine Carcinoma
Altered gene DLL3
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment SNC115
PhasePhase1
Recruitment statusRecruiting
TitleTo Evaluate the Safety and Pharmacokinetic of SNC115 Injections in Patients With Recurrent/Refractory Small Cell Lung Cancer and Lung Large Cell Neuroendocrine Crcinoma: an Open-label, Single-arm, Dose Escalation Exploratory Study
Year2024
CountryChina
Company sponsorShanghai Simnova Biotechnology Co.,Ltd.
Other ID(s)SNC115-DLL3 CART-101

Clinical Result

Cohort 1
Administration route infusion
Pts 35
Age Adult, Older_Adult
Lymph depletion Yes

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