Gene symbol | DLL3 | Synonyms | SCDO1 | Type of gene | protein-coding | |
Chromosome | 19 | Map location | 19q13.2 | dbXrefs | Entrez:10683 MIM:602768 HGNC:HGNC:2909 Ensembl:ENSG00000090932 AllianceGenome:HGNC:2909 | |
Gene perturbation-related omics dataset | PerturbAtlas | |||||
Description | delta like canonical Notch ligand 3 |
GTO ID | GTC3865 |
Trial ID | NCT06384482 |
Disease | Small Cell Lung Cancer | Lung Large Cell Neuroendocrine Carcinoma |
Altered gene | DLL3 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-NK cell |
Treatment | SNC115 |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | To Evaluate the Safety and Pharmacokinetic of SNC115 Injections in Patients With Recurrent/Refractory Small Cell Lung Cancer and Lung Large Cell Neuroendocrine Crcinoma: an Open-label, Single-arm, Dose Escalation Exploratory Study |
Year | 2024 |
Country | China |
Company sponsor | Shanghai Simnova Biotechnology Co.,Ltd. |
Other ID(s) | SNC115-DLL3 CART-101 |
Cohort 1 | |||||||||
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