Basic Information

Gene symbol CD70 Synonyms CD27-L, CD27L, CD27LG, LPFS3, TNFSF7, TNLG8A Type of gene protein-coding
Description CD70 molecule

GTO ID GTC3863
Trial ID NCT06383507
Disease Renal Cell Carcinoma | Ovarian Cancer | Cervix Cancer | Head and Neck Squamous Cell Carcinoma | Nasopharyngeal Carcinoma
Altered gene CD70
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CHT101
PhasePhase1
Recruitment statusNot Recruiting
TitleA Phase I Clinical Study to Assess the Safety and Efficacy of CD70-targeted CAR-T in the Treatment of CD70-positive Refractory or Relapsed Solid Tumors
Year2024
CountryChina
Company sponsorZhejiang University
Other ID(s)CHT101

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 3E6 cells/kg, 6E6 cells/kg, 8E6 cells/kg, 1E7 cells/kg
Pts 18
Age Adult, Older_Adult
Lymph depletion Yes

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