Basic Information

Gene symbol KLRK1 Synonyms CD314, D12S2489E, KLR, NKG2-D, NKG2D Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description killer cell lectin like receptor K1

GTO ID GTC3861
Trial ID NCT06379451
Disease Multiple Myeloma
Altered gene NKG2D
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment NKG2D CAR-NK cells
PhaseEarly_Phase1
Recruitment statusNot Recruiting
TitleAn Exploratory Clinical Study of the Safety and Efficacy of NKG2D Chimeric Antigen Receptor NK Cell Injections for the Treatment of Efractory Recurrent Multiple Myeloma
Year2024
CountryChina
Company sponsorChangzhou No.2 People's Hospital
Other ID(s)[2023]YLJSA088

Clinical Result

Cohort 1
Administration route infusion
Dosage 6E8 cells, 1E9 cells, 1.5E9 cells
Donor type autologous
Pts 9
Age Adult, Older_Adult

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