Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3859
Trial ID NCT06377228
Disease Lupus Nephritis
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment TAK-007
PhasePhase1
Recruitment statusNot Recruiting
TitleA Phase 1b, Open-Label, Multicenter Study to Evaluate the Safety and Efficacy of TAK-007, an Allogeneic Anti-CD19 Chimeric Antigen Receptor Natural Killer Cell (CD19 CAR-NK) Therapy, in Adult Subjects With Refractory Lupus Nephritis
Year2024
CountryJapan
Company sponsorTakeda
Other ID(s)TAK-007-1001

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 8E8 cells
Donor type Allogeneic
Pts 20
Age Adult, Older_Adult
Lymph depletion Yes

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