Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | CD3E | Synonyms | CD3epsilon, IMD18, T3E, TCRE | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11q23.3 | dbXrefs | |
Description | CD3 epsilon subunit of T-cell receptor complex |
GTO ID | GTC3855 |
Trial ID | NCT06373081 |
Disease | Systemic Lupus Erythematosus | Sjogren's Syndrome | Systemic Sclerosis | Inflammatory Myopathy | Vasculitis | Antiphospholipid Syndrome |
Altered gene | CD19|CD3E |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD19/CD3E CAR-T cells |
Phase | Not Applicable |
Recruitment status | Recruiting |
Title | A Clinical Study on the Safety and Efficacy of Anti-CD19-CD3E-CAR-T Cells in the Treatment of Relapsed or Refractory Autoimmune Disease |
Year | 2024 |
Country | China |
Company sponsor | Shanghai Changzheng Hospital |
Other ID(s) | CD19-CD3E-CN-A1 |
Cohort 1 | |||||||||||
|