Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD3E Synonyms CD3epsilon, IMD18, T3E, TCRE Type of gene protein-coding
Description CD3 epsilon subunit of T-cell receptor complex

GTO ID GTC3855
Trial ID NCT06373081
Disease Systemic Lupus Erythematosus | Sjogren's Syndrome | Systemic Sclerosis | Inflammatory Myopathy | Vasculitis | Antiphospholipid Syndrome
Altered gene CD19|CD3E
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD3E CAR-T cells
PhaseNot Applicable
Recruitment statusRecruiting
TitleA Clinical Study on the Safety and Efficacy of Anti-CD19-CD3E-CAR-T Cells in the Treatment of Relapsed or Refractory Autoimmune Disease
Year2024
CountryChina
Company sponsorShanghai Changzheng Hospital
Other ID(s)CD19-CD3E-CN-A1

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Pts 6
Age Adult, Older_Adult
Lymph depletion Yes

Relationship Graph

Overview of Knowledge Graph