Gene symbol | CLDN18 | Synonyms | SFTA5, SFTPJ | Type of gene | protein-coding |
Chromosome | 3 | Map location | 3q22.3 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | claudin 18 |
GTO ID | GTC3840 |
Trial ID | NCT06353152 |
Disease | Gastric Adenocarcinoma | Gastroesophageal-Junction Adenocarcinoma |
Altered gene | CLDN18 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CLDN18.2 CAR-T cells |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | An Early Exploratory Clinical Trial of Claudin18.2-Targeted Chimeric Antigen Receptor T Cell Therapy for Gastric/Gastroesophageal Junction Adenocarcinoma. |
Year | 2023 |
Country | China |
Company sponsor | Peking University |
Other ID(s) | GC506-507 |
Cohort 1 | |||||||||
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