Basic Information

Gene symbol CLDN18 Synonyms SFTA5, SFTPJ Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description claudin 18

GTO ID GTC3840
Trial ID NCT06353152
Disease Gastric Adenocarcinoma | Gastroesophageal-Junction Adenocarcinoma
Altered gene CLDN18
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CLDN18.2 CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitleAn Early Exploratory Clinical Trial of Claudin18.2-Targeted Chimeric Antigen Receptor T Cell Therapy for Gastric/Gastroesophageal Junction Adenocarcinoma.
Year2023
CountryChina
Company sponsorPeking University
Other ID(s)GC506-507

Clinical Result

Cohort 1
Administration route infusion
Pts 12
Age Adult, Older_Adult
Lymph depletion Yes

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