Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3838
Trial ID NCT06350110
Disease Systemic Lupus Erythematosus | Lupus Nephritis | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Granulomatous PolyangIItis | Microscopic PolyangIItis | Systemic Sclerosis | Idiopathic Inflammatory Myopathy | Sjogren's Syndrome
Altered gene BCMA|CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment BH002|BCMA/CD19 CAR-T cells
PhasePhase1|Phase2
Recruitment statusNot Recruiting
TitleT-cell Infusion Targeting BCMA and CD19 for Refractory/Relapsed Systemic Lupus Erythematosus (SLE) Patients With or Without Organs Involvement
Year2024
CountryChina
Company sponsorEssen Biotech
Other ID(s)ESBI202492

Clinical Result

Cohort 1
Administration route intravenous infusion
Pts 75
Age Adult, Older_Adult
Lymph depletion Yes

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