Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3837
Trial ID NCT06349343
Disease Systemic Lupus Erythematosus
Altered gene CD19|BCMA
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment BCMA/CD19 Hi-TCR-T cells
HLAHLA-independent
PhasePhase1
Recruitment statusNot Recruiting
TitleClinical Study of the Safety and Efficacy of CD19/BCMA HLA-independent TCR-T Cell Therapy for Refractory/Moderate-to-severe Systemic Lupus Erythematosus
Year2024
CountryChina
Company sponsorWuhan Union Hospital, China
Other ID(s)UHCT230949

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E6 cells/kg
Pts 20
Age Adult, Older_Adult

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