Basic Information

Gene symbol DLL3 Synonyms SCDO1 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description delta like canonical Notch ligand 3

GTO ID GTC3836
Trial ID NCT06348797
Disease Small Cell Lung Cancer
Altered gene DLL3
Therapeutic/Target gene Therapeutic gene
TherapyCAR-T cell
Treatment BHP01
PhasePhase1
Recruitment statusNot Recruiting
TitlePhase I Clinical Study on Safety and Feasibility of DLL3 Targeted α-PD-L1/4-1BB Modifying Chimeric Antigen Receptor T-cells in Patients With Relapsed or Refractory Small Cell Lung Cancer (SCLC)
Year2024
CountryChina
Company sponsorSichuan University
Other ID(s)BHP01-01

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 5E5 cells/kg
Pts 28
Age Adult, Older_Adult
Lymph depletion Yes

Relationship Graph

Overview of Knowledge Graph