Basic Information

Gene symbol CD276 Synonyms 4Ig-B7-H3, B7-H3, B7H3, B7RP-2 Type of gene protein-coding
Description CD276 molecule

GTO ID GTC3833
Trial ID NCT06347068
Disease Breast Cancer | Triple Negative Breast Cancer
Altered gene CD276
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment iC9-CAR.B7-H3 T cells
PhasePhase1
Recruitment statusNot Recruiting
TitleStudy of Administration of T Cells Expressing B7-H3 Specific Chimeric Antigen Receptors and Containing the Inducible Caspase 9 Safety Switch in Subjects With Triple Negative Breast Cancer
Year2024
CountryUnited States
Company sponsorUNC Lineberger Comprehensive Cancer Center
Other ID(s)LCCC2128-ATL

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type autologous
Pts 42
Age Adult, Older_Adult
Lymph depletion Yes

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