Gene symbol | CD276 | Synonyms | 4Ig-B7-H3, B7-H3, B7H3, B7RP-2 | Type of gene | protein-coding |
Chromosome | 15 | Map location | 15q24.1 | dbXrefs | |
Description | CD276 molecule |
GTO ID | GTC3833 |
Trial ID | NCT06347068 |
Disease | Breast Cancer | Triple Negative Breast Cancer |
Altered gene | CD276 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | iC9-CAR.B7-H3 T cells |
Phase | Phase1 |
Recruitment status | Not Recruiting |
Title | Study of Administration of T Cells Expressing B7-H3 Specific Chimeric Antigen Receptors and Containing the Inducible Caspase 9 Safety Switch in Subjects With Triple Negative Breast Cancer |
Year | 2024 |
Country | United States |
Company sponsor | UNC Lineberger Comprehensive Cancer Center |
Other ID(s) | LCCC2128-ATL |
Cohort 1 | |||||||||||
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