Basic Information

Gene symbol MICA Synonyms MIC-A, PERB11.1 Type of gene protein-coding
Description MHC class I polypeptide-related sequence A

Gene symbol MICB Synonyms PERB11.2 Type of gene protein-coding
Description MHC class I polypeptide-related sequence B

GTO ID GTC3827
Trial ID NCT06342986
Disease Gynecologic Cancer | Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cavity Cancer
Altered gene MICA|MICB
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment FT536
PhasePhase1
Recruitment statusRecruiting
TitleIntraperitoneal FT536 in Recurrent Ovarian, Fallopian Tube, and Primary Peritoneal Cancer
Year2024
CountryUnited States
Company sponsorMasonic Cancer Center, University of Minnesota
Other ID(s)2023LS185|P01CA111412

Clinical Result

Cohort 1
Administration route intraperitoneal injection
Dosage 3E6 cells/dose, 1E8 cells/dose, 3E8 cells/dose, 1E9 cells/dose
Donor type Allogeneic
Pts 33
Age Adult, Older_Adult
Lymph depletion Yes

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