Basic Information

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC3824
Trial ID NCT06340737
Disease Follicular Lymphoma | Mantle Cell Lymphoma | Hairy Cell Leukemia | Lymphoplasmacytic Lymphoma | Burkitt Lymphoma | Marginal Zone Lymphoma | Waldenstrom Macroglobulinemia
Altered gene CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD22 CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitlePhase Ib Clinical Trial of Autologous CD22 Chimeric Antigen Receptor (CAR) T Cells in Adults With Recurrent or Refractory B Cell Lymphomas
Year2024
CountryUnited States
Company sponsorStanford University
Other ID(s)IRB-73394

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Pts 120
Age Adult, Older_Adult
Lymph depletion Yes

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