Basic Information

Gene symbol GPRC5D Synonyms None Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description G protein-coupled receptor class C group 5 member D

GTO ID GTC3819
Trial ID NCT06333509
Disease Multiple Myeloma | Primary Plasma Cell Leukemia
Altered gene GPRC5D
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CT071
PhasePhase1|Phase2
Recruitment statusNot Recruiting
TitleA Phase 1/2 Open Label Study to Evaluate the Safety and Efficacy of CT071, an Autologous Anti-GPRC5D CAR T, in Relapsed/Refractory Multiple Myeloma (RRMM) or Relapsed/Refractory Primary Plasma Cell Leukemia (RRpPCL)
Year2024
CountryChina
Company sponsorCARsgen Therapeutics Co., Ltd.
Other ID(s)CT071-HM-01

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Pts 166
Age Adult, Older_Adult
Lymph depletion Yes

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