Gene symbol | GPRC5D | Synonyms | None | Type of gene | protein-coding | |
Chromosome | 12 | Map location | 12p13.1 | dbXrefs | Entrez:55507 MIM:607437 HGNC:HGNC:13310 Ensembl:ENSG00000111291 AllianceGenome:HGNC:13310 | |
Gene perturbation-related omics dataset | PerturbAtlas | |||||
Description | G protein-coupled receptor class C group 5 member D |
GTO ID | GTC3819 |
Trial ID | NCT06333509 |
Disease | Multiple Myeloma | Primary Plasma Cell Leukemia |
Altered gene | GPRC5D |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CT071 |
Phase | Phase1|Phase2 |
Recruitment status | Not Recruiting |
Title | A Phase 1/2 Open Label Study to Evaluate the Safety and Efficacy of CT071, an Autologous Anti-GPRC5D CAR T, in Relapsed/Refractory Multiple Myeloma (RRMM) or Relapsed/Refractory Primary Plasma Cell Leukemia (RRpPCL) |
Year | 2024 |
Country | China |
Company sponsor | CARsgen Therapeutics Co., Ltd. |
Other ID(s) | CT071-HM-01 |
Cohort 1 | |||||||||||
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