Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3818
Trial ID NCT06333483
Disease Systemic Lupus Erythematosus
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment obe-cel|Obecabtagene autoleucel|AUTO1
PhasePhase1
Recruitment statusRecruiting
TitleA Single-Arm, Open-Label, Phase I Study to Determine the Safety, Tolerability and Preliminary Efficacy of Obecabtagene Autoleucel in Patients With Severe, Refractory Systemic Lupus Erythematosus
Year2024
CountrySpain|United Kingdom
Company sponsorAutolus Limited
Other ID(s)AUTO1-SL1|2023-508236-60-00

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Pts 12
Age Adult, Older_Adult
Lymph depletion Yes

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