Basic Information

Gene symbol CD70 Synonyms CD27-L, CD27L, CD27LG, LPFS3, TNFSF7, TNLG8A Type of gene protein-coding
Description CD70 molecule

GTO ID GTC3813
Trial ID NCT06326463
Disease Hematological Malignancy | Acute Lymphoblastic Leukemia | Acute Myeloid Leukemia
Altered gene CD70
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD70 CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitleCAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies
Year2024
CountryUnited States
Company sponsorSt. Jude Children's Research Hospital
Other ID(s)DIRECT70|NCI-2024-03240

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type autologous
Pts 24
Age Child, Adult
Lymph depletion Yes

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