Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC3811
Trial ID NCT06326008
Disease B-Cell Acute Lymphoblastic Leukemia | Acute Lymphoblastic Leukemia
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD22 CAR-T cells
PhasePhase1
Recruitment statusNot Recruiting
TitleSafety, Tolerability and Pharmacokinetics of Donor-derived CD19 CAR Therapy Bridged Allogeneic Haematopoietic Stem Cell Transplantation and Sequential Donor-derived CD22 CAR Therapy in Refractory or Relapsed B Cell Acute Lymphoblastic Leukemia: a Clinical Trial
Year2024
CountryChina
Company sponsorBeijing GoBroad Hospital
Other ID(s)BJGBYY-IIT-LCYJ-2023-002

Clinical Result

Cohort 1
Administration route infusion
Donor type Allogeneic
Pts 48
Age Child, Adult

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